Yes, certain medications can cause gynecomastia, which is the enlargement of
male breast tissue. Medications that can cause gynecomastia include some antidepressants, antipsychotics, and medications used to treat prostate cancer. Other medications, such as those used to treat heart disease, can also cause hormonal imbalances that may lead to gynecomastia. Illegal drugs such as marijuana and anabolic steroids can also cause gynecomastia. If a person is taking a medication that may be causing gynecomastia, it is important to talk to their healthcare provider to discuss alternative treatment options or ways to manage the side effects.